Although Claude Puel is right to have rotated his squad in recent weeks and indeed is now in a very busy period, if he puts out a good team against Inter Milan we could find ourself on the cusp of qualifying from the group.
This is not a criticism of Claude Puel's squad rotation policy, far from it I have often said how well he has worked it, however sometimes you have to do a little less rotating and the trip to Inter Milan could well be one of those games.
Although Inter are in turmoil at the moment with the manager and certain players under fire from the fans, the fact still remains they are a formidable side at home and we cannot underestimate them.
If we can go to the San Siro and win then we would not only almost certainly be top of the group and perhaps only one home win away from qualification.
This would be a big achievement for the club and we need to be putting out a fairly decent side.
To make matter worse at the back we are going to be without both first choice full backs and indeed the second choice left back, so it is important that we do not make the situation worse, we need both Virgil Van Dijk and Jose Fonte in for this one.
In midfield it's not so much of a problem as we have the likes of Pierre Emile Hojbjerg and James Ward Prowse on the bench from Sunday and fresh, both are likely to play.
Perhaps the biggest issue though is whether Charlie Austin plays or not, my thoughts are that he should, he is in form and perhaps the fact that Puel substituted him against Burnley with 20 minutes to go when he was in with a good chance of a hat trick is indication that he intends him to play some part in this game.
Sometimes you have to throw players into tough periods, they are very fit and should not have a problem playing three games in a short period every once in a while, of course they cant do this over prolonged periods, but every now and then it's needed to see us through important matches.
I trust Claude Puel to get things right, he has shown us that he knows what he is doing and has earned that trust, however I want us to take this game very seriously and not only make this a great night to remember for the 7,000 travelling Saints supporters, but one of the great nights in our history and a win would certainly do that and as I said earlier put us on the cusp of qualification.